Impact of resistance training on fat distribution in people living with HIV: randomized clinical trial

Keywords: Anthropometry, Exercise, HIV infection, Acquired Immunodeficiency Syndrome

Abstract

To verify the impact of eight weeks of resistance training (RT) on body fat distribution of people living with human immunodeficiency virus (HIV) (PLH). Seventeen randomized PLH participated in two groups: control (CG, n=6) and training (TG, n=11). The protocol of RT consisted of ten exercises. The subjects' triceps, subscapular, abdominal, thigh, and leg skinfolds were assessed before and after the training period. The analysis indicated significant differences (p<0.05) between the groups after the period of intervention, with decreased subcutaneous fat in the TG and increased subcutaneous fat in the CG in the areas of the torso (-3.77%, 12.97%) and limbs (-10.28%, 10.08%). By calculating the sum of skinfolds, the TG had an average reduction of 6.43%, while the CG increased by 11.12% after the eight weeks, with significant differences between the groups (p<0.05). Eight weeks of RT decreased subcutaneous body fat in PLH.

Author Biographies

Kauana Borges Marchini, Universidade Estadual de Maringá - UEM
PhD student in physical activity and health in Physical Education Post- graduate Program Associated UEM/UEL, State University of Maringa (UEM), Maringa (PR), Brazil.
Rafael Lóde Cortez, Universidade Estadual de Maringá - UEM
Bachelor of Physical Education, State University of Maringa (UEM), Maringa (PR), Brazil.
Pollyana Mayara Nunhes, Universidade Estadual de Maringá - UEM
PhD student in physical activity and health in Physical Education Postgraduate Program Associated UEM/UEL, State University of Maringa (UEM), Maringa (PR), Brazil.
Dayane Cristina de Souza, Universidade Estadual do Oeste do Paraná - UNIOESTE
PhD in Physical Education from the State University of Maringa (UEM). Collegiate Professor of the Physical Education Course, State University of Western Parana, Marechal Candido Rondon (PR), Brazil.
Abel Felipe Freitag, Universidade Estadual de Maringá - UEM
PhD student in physical activity and health in Physical Education Postgraduate Program Associated UEM/UEL, State University of Maringa (UEM), Maringa (PR), Brazil.
Ademar Avelar, Universidade Estadual de Maringá - UEM
PhD in Physical Education from the State University of Londrina (UEL). Associate Professor and Permanent Professor of Physical Education Postgraduate Program Associated UEM/UEL, State University of Maringa (UEM), Maringa (PR), Brazil.

References

1. Mattevi VS, Tagliari CF. Pharmacogenetic considerations in the treatment of HIV. Pharmacogenomics. 2017;18(1):85–98.

2. Boyd AT, Oboho I, Paulin H, Ali H, Godfrey C, Date A, et al. Addressing advanced HIV disease and mortality in global HIV programming. AIDS Res Ther [Internet]. 2020;17(1):1–7. Available from: https://doi.org/10.1186/s12981-020-00296-x

3. Savvoulidis P, Butler J, Kalogeropoulos A. Cardiomyopathy and Heart Failure in Patients With HIV Infection. Can J Cardiol [Internet]. 2019; Available from: https://doi.org/10.1016/j.cjca.2018.10.009

4. Guimarães NS, Raposo MA, Greco D, Tupinambás U, Premaor MO. People Living With HIV, Lean Mass, and Sarcopenia: A Systematic Review and Meta-Analysis. J Clin Densitom. 2021;

5. Zanetti HR, Lopes LTP, Gonçalves A, Soares VL, Soares WF, Hernandez A V., et al. Effects of resistance training on muscle strength, body composition and immune-inflammatory markers in people living with HIV: a systematic review and Meta-analysis of randomized controlled trials. HIV Res Clin Pract [Internet]. 2021;22(5):119–27. Available from: https://doi.org/10.1080/25787489.2021.1975448

6. Beraldo RA, Meliscki GC, Silva BR, Navarro AM, Bollela VR, Schmidt A, et al. Anthropometric measures of central adiposity are highly concordant with predictors of cardiovascular disease risk in HIV patients. Am J Clin Nutr. 2018;107(6):883–93.

7. Almeida MRCB, Labronici L. A trajetória silenciosa de pessoas portadoras do HIV contada pela história oral TT - The silent itinerary of people with HIV told through oral history. Ciência & Saúde Coletiva [Internet]. 2007;12(1):263–74. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232007000100030&lang=pt%0Ahttp://www.scielo.br/pdf/csc/v12n1/26.pdf

8. Lamb KM, Nogg KA, Safren SA, Blashill AJ, Diego S, Gables C. Mechanism of Change in Cognitive Behavioral Therapy for Body Image and Self-Care on ART Adherence Among Sexual Minority Men Living with HIV. AIDS Behav. 2019;22(8):2711–7.

9. Soares LR, Casseb JS do R, Chaba DC da S, Batista LO, Sousa LV de A, Fonseca FLA. Self-reported lipodystrophy, nutritional, lipemic profile and its impact on the body image of HIV-1-infected persons, with and without antiretroviral therapy. AIDS Care - Psychol Socio-Medical Asp AIDS/HIV [Internet]. 2020;32(10):1317–22. Available from: https://doi.org/10.1080/09540121.2019.1687832

10. Fontenele MSM, Cunha GH da, Lopes MV de O, Siqueira LR, Lima MAC, Moreira LA. Development and evaluation of a booklet to promote ealthy lifestyle in people with HIV. Rev Bras Enferm. 2021;74Suppl 5(74Suppl 5):e20200113.

11. Fleck SJ, Kraemer WJ. Fundamentos do Treinamento de Força Muscular. Artmed Editora; 2017.

12. Poton R, Polito M, Farinatti P. Effects of resistance training in HIV-infected patients: A meta-analysis of randomised controlled trials. J Sports Sci [Internet]. 2017;35(24):2380–9. Available from: http://dx.doi.org/10.1080/02640414.2016.1267389

13. O’Brien K, Tynan AM, Nixon S, Glazier RH. Effects of progressive resistive exercise in adults living with HIV/AIDS: Systematic review and meta-analysis of randomized trials. AIDS Care - Psychol Socio-Medical Asp AIDS/HIV. 2008;20(6):631–53.

14. Leach L., Bassett S., Smithdorf G, Andrews B., Travill A. A Systematic Review of the Effects of Exercise Interventions on Body Composition in HIV+ Adults. Open AIDS J. 2015;9(1):66–79.

15. Mussoi TD. Avaliação Nutricional na Prática Clínica: da gestação ao envelhecimento. 1 ed. Rio de Janeiro: Guanabara Koogan; 2014.

16. Grace JM, Semple SJ, Combrink S. Exercise therapy for human immunodeficiency virus/AIDS patients: Guidelines for clinical exercise therapists. J Exerc Sci Fit [Internet]. 2015;13(1):49–56. Available from: http://dx.doi.org/10.1016/j.jesf.2014.10.003

17. Rodrigues C, Rocha P. Musculação: teoria e prática. Rio de Janeiro: Sprint; 1985.

18. Cohen J. A power primer. Psychol Bull. 1992;112(1):155.

19. Spence DW, Galantino MLA, Mossberg KA, Zimmerman SO. Progressive resistance exercise: Effect on muscle function and anthropometry of a select AIDS population. Vol. 71, Archives of Physical Medicine and Rehabilitation. 1990. p. 644–8.

20. Bessa A, Lopez JC, Di Masi F, Ferry F, Silva GC, Dantas EHM. Lymphocyte CD4+ cell count, strength improvements, heart rate and body composition of HIV-positive patients during a 3-month strength training program. J Sports Med Phys Fitness. 2017;57(7–8):1051–6.

21. Brito-neto JG De, Andrade MF De, Almeida VD De, Carla D, Paiva C, Morais NM De, et al. Strenght training improves bod composition, muscle strength and increases CD4+ T lymphocyte levels in people living with HIV/AIDS. 2019;11.

22. McArdle WD, Katch FI, Katch VL. Fisiologia do exercício. Wolters Kluwer Health; 2015.

23. Vancampfort D, Mugisha J, Richards J, De Hert M, Lazzarotto AR, Schuch FB, et al. Dropout from physical activity interventions in people living with HIV: a systematic review and meta-analysis. AIDS Care - Psychol Socio-Medical Asp AIDS/HIV [Internet]. 2017;29(5):636–43. Available from: http://dx.doi.org/10.1080/09540121.2016.1248347

24. Bailin SS, Gabriel CL, Wanjalla CN, Koethe JR. Obesity and Weight Gain in Persons with HIV. Curr HIV/AIDS Rep. 2020;17(2):138–50.

25. Matheus SC, Santos L dos, Behenck MS, Both DR. O uso da antropometria para avaliar a distribuição de gordura corporal de pacientes com HIV / AIDS Use of anthropometry to assess body fat distribution of patients with HIV /. arq ciênc Saúde. 2015;22(5):64–9.

26. Gomes-Neto M, Conceicao C, Carvalho V, Brites C. A systematic review of the effects of different types of therapeutic exercise on physiologic and functional measurements in patients with HIV/AIDS. Clinics. 2013;68(8):1157–67.

Published
2022-08-12
Section
Artigos Originais