PREVALENCE OF GENOTYPES OF HEPATITIS C VIRUS IN THE NORTH-WESTERN MACRO-REGION OF THE STATE OF PARANÁ, BRAZIL

  • Amanda Milene Malacrida Universidade Estadual de Maringá http://orcid.org/0000-0003-1271-1355
  • Sonia Kaori Miyamoto
  • Hellen Capellari Menezes
  • Maria Ferreira dos Santos Neta Universidade Estadual de Maringá
  • Dennis Armando Bertolini
Keywords: Hepatitis C, Genotype, Geographic distribution, Epidemiology.

Abstract

The prevalence of hepatitis C is wide due to great differentiation of genotypes. Current study verifies HCV genotypes in patients with chronic Hepatitis C in the northwestern microregion of the state of Paraná, Brazil. Current transversal study analyzed laboratory data of patients attended to in a clinical test laboratory between August 2013 and October 2015. Study verified the distribution of patients suffering from chronic HCV according to gender and age bracket and to the laboratory attendance range. Results were compared with those in the literature. Results showed that 210 (60.3%) out of 348 samples belonged to genotype 1 (p<0.05), 101 (29.0%) to 3 (p<0.05), 21 (6.0%) to 2, 1 (0.3%) to 4, 1 (0.3%) to 5 and 12 (3.4%) undetermined. The cities with the highest detection of Hepatitis C were: Maringá (112 cases/32.2%), Cascavel (59 cases/17.0%), Paranavaí (37 cases/10.6%) and Umuarama (22 cases /6.3%). Most prevalent genotypes were 1, 3 and 2, with males as the most affected and the greatest occurrence was featured within age bracket 40 – 50 years.

Author Biography

Amanda Milene Malacrida, Universidade Estadual de Maringá
Ciências da Saúde/ Biomedicina
Published
2016-10-07
Section
Artigos Originais