Impact of vaginal estrogenization in follow-up of oncotic cytology of undetermined significance in postmenopausal women

Keywords: Atypical squamous cells of the cervix, Estriol, Menopause, Squamous intraepithelial lesions of the cervix

Abstract

Current paper evaluates topic vaginal estrogenization following oncotic cytology of undetermined significance, type ASC-H, in postmenopausal women. A case-control study evaluated menopausal women diagnosed with ASC-H, divided into two groups, with and without the use of topic vaginal estrogen (GE and GNE). Odds ratios were calculated from contingency tables built with robust variation. 128 medical records were analyzed, 27% of which were from the GNE and 72% from the GE. There was an increase in ASC-H diagnoses in GNE. In GE, approximately 68 times less inappropriate colposcopies and a decrease in the number of colposcopies and High Frequency Surgery (HFS), with a reduction of 21 and 12.5 times, respectively. Decrease in the number of colposcopies with better adaptation to the exam, unchanged number of biopsies and decrease in the number of high-frequency surgeries, in the group using topic vaginal estrogen during the follow-up.

Author Biographies

Natacha Machado de Araújo , Universidade da Região de Joinville - UNIVILLE
Master in Health and Environment from the University of the Region os Joinville - UNIVILLE ; Professor of the Undergraduate course in Medicine at the University of the Region of Joinville – UNIVILLE; Coordinator and Preceptor of Gynecology in the Medical Residency Program in Gynecology and Obstetrics at Darcy Vargas Maternity; Coordinator of the Lower Genital Tract Pathology Clinic at the Hans Dieter Schmidt Regional Hospital - Joinville (SC), Brazil.
Jean Carl Silva , Universidade da Região de Joinville - UNIVILLE
PhD in Medical Sciences (UNIFESP/SP); Professor of the Undergraduate course in Medicine and the Graduate Program in Health and Environment at the University of the Region of Joinville – UNIVILLE, Joinville (SC), Brazil.
Larissa Maria Moreira, Universidade da Região de Joinville - UNIVILLE
Undergraduate student of the Medicine course at the University of the Region of Joinville - UNIVILLE, Joinville (SC), Brazil.
Nayme Hechem Monfredini , Universidade da Região de Joinville - UNIVILLE
Undergraduate student of the Medicine course at the University of the Region of Joinville - UNIVILLE, Joinville (SC), Brazil.

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Published
2020-11-24
Section
Artigos Originais