Evaluation of the Effects of Different Doses of Caffeine During Pregnancy in an Experiment with Rats
Keywords:
Caffeine, Pregnancy, Neonates
Abstract
Eleven pregnant female rats were divided into control and experimental group. Control group comprised two female rats intaking only water and experimental groups with three rats each with several concentrations of caffeine in water at 21.5 mg, 1g and 5 g/100g animal/weight. During pregnancy, the female rats were weighed daily to verify whether different caffeine concentrations interfered in the variable. Neonates of the control group were born alive whereas some neonates in the experimental groups which ingested different caffeine concentrations were dead. Cannibalism by the dame and re-absorption of neonates into the womb occurred. Only three neonates were alive. Results show that the number of still birth increased and live fetuses decreased according to the three doses administered, when compared to the control group. A greater proportion of re-absorptions occurred in experimental groups, greater still with concentration 1mg/100g weight.
Published
2013-12-02
Section
Publicações Temáticas
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