Adherence to antiretroviral therapy during the COVID-19 pandemic in a referral service

Adesão à terapia antirretroviral durante a pandemia de COVID-19 em um serviço de referência

Authors

DOI:

https://doi.org/10.17765/2176-9206.2025v18e12785

Keywords:

HIV, Antiretroviral Therapy, Highly Active, Medication Adherence, COVID-19

Abstract

 

Objective: Evaluate the impact of the pandemic on adherence to antiretroviral therapy in people living with HIV. Method: An observational study was conducted, using data from the Medication Logistics Control System and physical records of 117 patients from a pharmacy linked to a tertiary hospital. Two periods were examined, one pre-pandemic and one during the COVID-19 pandemic. Adherence to antiretroviral therapy was assessed by comparing medication withdrawal with the expected time frame. Results: The majority of patients were adherent before (60.7%) and during (62.4%) the pandemic. Most patients maintained undetectable viral load and LT-CD4+ count above 350 cells/mm³ in both periods. Conclusion: the COVID-19 pandemic did not negatively impact adherence to antiretroviral therapy, and there was no difference in viral and immunological parameters before and during the COVID-19 pandemic.

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Author Biographies

Larissa Rodrigues Borges, Faculty of Medicine of Marília

Graduanda em medicina pela Faculdade de Medicina de Marília - FAMEMA, Marília (SP), Brasil.

Maria Carolina Paraluppi, Faculty of Medicine of Marília

Graduated in medicine from the Faculty of Medicine of Marília in early 2023. Currently working as an on-call doctor at Hospital Cantareira in São Paulo, with an emphasis on psychiatry. Start of postgraduate studies in psychiatry in the second semester of 2024.

Anna Carolina Scola, Faculty of Medicine of Marília

Graduated in Medicine, in 2022, from the Faculty of Medicine of Marília (FAMEMA) who obtained an A grade in ENADE 2019 for her Medicine and Nursing courses, participated in the internships of: Clinical Medicine and Cardiology at the Faculty of Medicine of Marília (2018 ); Acupuncture at the Brazilian Acupuncture Medical Association (2019); Gynecology and Obstetrics at Hospital Maternidade Leonor Mendes de Barros (2020); Family and Community Medicine at the Vila Ramos Basic Health Unit? Freguesia do Ó (2021); and, Medical Clinic and Geriatrics at the Dom Pedro II Geriatric and Convalescent Hospital (2022); Radiology and Imaging Diagnosis (2022). She joined the 2018 Management of the Scientific Society of Gynecology and Obstetrics (SOCIGO) as a Member. She joined the Scientific Society of Pulmonology (SOCIP) as a Member (2018, 2019 and 2021), as Scientific Coordinator and Deputy General Coordinator in 2019 and as Administrative Coordinator in 2020. She joined the Academic League of Clinical Medicine (LACM) as a Member ( 2020). She completed the Advanced Cardiac Life Support (ACLS) course. She received the "Academic Merit" award in recognition of her academic performance in the 51st Class of the Medicine course at the Faculty of Medicine of Marília (2022).

Letícia Chuman, Faculty of Medicine of Marília

Graduated in medicine from the Faculty of Medicine of Marília - FAMEMA, Marília (SP), Brazil.

Ana Carolina Nonato, Faculty of Medicine of Marília

PhD student in the Postgraduate Program in Public Health (PPGSC) at the Faculty of Medicine of the University of São Paulo (FMUSP, 2024-)Graduation in Medicine from the Faculty of Medicine of Marília (2014-2019). Master's degree from the Professional Master's program "Teaching in Health" at the Faculty of Medicine of Marília (2020-2022). Postgraduate degree in Health Management from the institution VerboMed (2020-2021) and in Human Rights from Faculdade Focus (2021-2022) .Volunteer professor at the Public Health Center at the Faculty of Medicine of Marília (2021-January/2024)

Osni Lázaro Pinheiro, Faculty of Medicine of Marília

He has a degree in Pharmacy and Biochemistry (1990) and a specialization in Pharmacology (1991-1992) from the University of Sagrado Coração, a master's degree in Biological Sciences (Pharmacology) from the Universidade Estadual Paulista Júlio de Mesquita Filho (1997) and a doctorate in Gynecology, Obstetrics and Mastology from Universidade Estadual Paulista Júlio de Mesquita Filho (2002). He is a professor at the Faculty of Medicine of Marília, in the discipline of Pharmacology and Experimental Therapeutics (1995 to date). He coordinated the Postgraduate Program in Health Education (PPGES)-Professional Master's Degree at the Faculty of Medicine of Marília (2011-2021), being a permanent professor at PPGES since its implementation (2011) until the present moment. He is currently Director of Postgraduate Studies and Research at Famema (management 2021-2025).

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Published

2024-07-18

How to Cite

Borges, L. R., Paraluppi, M. C., Scola, A. C., Chuman, L., Nonato, A. C., & Pinheiro, O. L. (2024). Adherence to antiretroviral therapy during the COVID-19 pandemic in a referral service: Adesão à terapia antirretroviral durante a pandemia de COVID-19 em um serviço de referência. Saúde E Pesquisa, 18, e12785. https://doi.org/10.17765/2176-9206.2025v18e12785

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