Prevalência de Candida sp. em sanitários de hospitais e sua sensibilidade aos antifúngicos comerciais  : Prevalence of Candida sp. in Hospital Toilets and Their Sensitivity to Commercial Antifungals

Ivisson Lucas Campos da  Silva; Marcia dos Santos  Rizzo; Jandson Vieira  Costa; Diane Nogueira Paranhos  Amorim

doi:10.17765/2176-9206.2025v18e13187

Authors

Ivisson Lucas Campos da Silva Facid Wyden University Center https://orcid.org/0000-0003-2848-9402
Marcia dos Santos Rizzo Federal University of Piauí https://orcid.org/0000-0003-4276-3113
Jandson Vieira Costa Facid Wyden University Center https://orcid.org/0000-0003-3448-670X
Diane Nogueira Paranhos Amorim Facid Wyden University Center https://orcid.org/0000-0002-5362-5747

DOI:

https://doi.org/10.17765/2176-9206.2025v18e13187

Keywords:

Candidiasis, Fungal Infections, Hospital Environments, Infection Control, Sensitivity to Antifungals

Abstract

Objective: To evaluate the prevalence of species of the genus Candida in toilet seats of public and private hospitals in Teresina-PI and to assess their sensitivity profile to antifungals. Method: Eight samples were analyzed in duplicates from the surfaces of male and female toilet seats. Results: Candida yeasts were detected in 18.75% of the samples, with 6.25% identified as C. krusei and 12.5% as C. glabrata. Both species showed significant inhibition by the antifungals ketoconazole and nystatin, with nystatin exhibiting the largest halo diameter and greater effectiveness. However, variations in variance and standard deviation data were observed. In lower concentrations, the inhibition of fluconazole and nystatin was reduced. Conclusion: The presence of these species in hospital environments highlights the need for rigorous monitoring and control to prevent fungal infections, contributing to the reduction of morbidity and mortality associated with these infections.

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Author Biographies

Ivisson Lucas Campos da Silva, Facid Wyden University Center

Technological Sciences of Piauí - UNINOVAFAPI (2014). Graduating in Pharmacy from the Facid Wyden University Center. Specialist in Microbiology Applied to Health Sciences from the Federal University of Piauí - UFPI (2015). Specialist in Advanced Aesthetics from the Monte Pascoal Institute. Master in Sciences and Health from the Federal University of Piauí - UFPI (2018). PhD in Pharmaceutical Sciences from the Federal University of Piauí - UFPI. He has experience in the areas of genotoxicity, hematology, biochemistry, parasitology, environmental analysis, microbiology, epidemiology, aesthetics and public health. He worked as a biomedical scientist at the Megalab laboratory, at the Testing and Counseling Center (CTA), at the Einstein Education System, at the Faculty of Higher Education of Piauí (FAESPI), at Aprovação Cursos and at Faculdade Sucesso (formerly ISEPRO). He is currently a professor and coordinator of the Biomedicine course at Centro Universitário Facid Wyden (UNIFACID).

Marcia dos Santos Rizzo, Federal University of Piauí

Graduated in Veterinary Medicine from the Faculty of Agricultural and Veterinary Sciences of Jaboticabal, São Paulo State University "Júlio de Mesquita Filho" (FCAVJ - UNESP, 1988), with specialization in Experimental Pathology from the Faculty of Veterinary Medicine and Animal Science of the University of São Paulo (FMVZ-USP, 1990), Master's degree (1994) and PhD (2000) from the University of São Paulo (USP), area of concentration Experimental and Comparative Pathology, in the thematic area of metastasis mechanisms and tumor immunology. She is currently Associate Professor IV of the Department of Morphology (DMOR / CCS) of the Federal University of Piauí (UFPI). Researcher at the Laboratory of Biological Analysis of Materials (LABMAT - LIMAV) and collaborator of the PPG in Materials Science and Engineering. Professor and advisor (permanent member) of the Graduate Program in Health Sciences and the Graduate Program in Pharmaceutical Sciences at UFPI. Leader of the Research Group entitled "Pathobiology of Cell Differentiation" and linked to the research areas in experimental models of lung and kidney diseases associated with cell therapy, experimental tumors, and biomaterials and active constituents in inflammation and tissue repair. She has experience in the area of Experimental and Comparative Pathology, with emphasis on inflammation, tissue regeneration/healing with new therapeutic devices, cytotoxic activity, angiogenesis, toxicity of natural products in vitro and new therapeutic drugs, alveolar and peritoneal macrophage activity and in vitro and in vivo studies with experimental tumors and Immunomodulation, in addition to studies on Visceral Leishmaniasis.

Jandson Vieira Costa, Facid Wyden University Center

Agricultural Engineer from the State University of Piauí - UESPI (2011). Master (2014) and Doctor (2020) in Animal Science from the Federal University of Piauí - UFPI, in the research line: Evaluation, Conservation and Management of Pastures in the Tropics. The referred program was evaluated by CAPES and became known as ZOOTECNIA TROPICAL through Process SEI 23038.013744/2019-81 with the date of signature of the DAV approval letter: 09/27/2019 and registered on 05/03/2021. He has experience as a teacher in technical and higher education. He is a full professor I at the Facid Wyden University Center, of the courses of Civil, Electrical, Mechanical and Production Engineering, Architecture, Biomedicine, Pharmacy and Veterinary Medicine. Professor of the Master's Degree in Biotechnology at the Facid Wyden University Center and Substitute Professor of the Agronomy and Animal Science courses. In addition to teaching in the Agronomy and Animal Science courses, he participated and developed works with an emphasis on the development of sustainable technologies, such as alternative materials for civil construction, non-conventional food plants (PANCs). He works specifically with the production of tropical forages, in addition to evaluations in behavioral activities of small ruminants. He participated and developed works in animal production with an emphasis on forage production systems and in the area of animal health. He coordinates the Study Group on Tropical Pastures GePAT, with projects that monitor the development and adaptation of forages to the environmental conditions of Piauí. Currently, in addition to teaching, he is the Editor-in-Chief of the FACID Magazine: Ciência Vida and Coordinator of Research, Extension and Internationalization at UNIFACID.

Diane Nogueira Paranhos Amorim, Facid Wyden University Center

PhD in Gerontology from the Catholic University of Brasília (2020). Master's degree in Gerontology from the Catholic University of Brasília (2016). Specialization in Public Health from Faculdade Integral Diferencial - FACID / DEVRY (2016). Specialization in Manual and Postural Therapy from the Maringá University Center - School of Manual and Postural Therapy (2013). Physiotherapist graduated from Faculdade Integral Diferencial (2012). Has experience in the area of Academic Management, Higher Education Teaching, Outpatient, Community, Gerontological Physiotherapy and Public Health. Professor of the Master's Degree in Biotechnology at Centro Universitário Facid Wyden.

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