Characteristics and factors related to tramadol abuse: an integrative review

Características e fatores relacionados ao abuso de tramadol: uma revisão integrativa

Authors

DOI:

https://doi.org/10.17765/2176-9206.2025v18e13273

Keywords:

Tramadol, Abuse, Integrative review

Abstract

The evidence found in the literature on the abusive use of tramadol and its motivations was described. This is an integrative review carried out in the PubMed, Scopus and Virtual Health Library databases, using the descriptors "tramadol" and "abuse". Eleven studies were selected, published between January 1, 2013 and December 31, 2022, and 82% of these were from African countries. The individuals who abused tramadol were predominantly male, aged between 13 and 45 years, and in 63% of the studies, they had at least a high school education and in 72.2% they worked. The motivations were: influence of friends, pain relief, improvement of mood and sexual performance. Regarding tramadol dependence, 45.45% of the individuals were in treatment. The results of the review mainly reflect the situation of some African countries that have a notable abusive use of tramadol

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Author Biographies

Maira Jeane Silva, Universidade Federal do Ceará

Farmacêutica pela Universidade Federal do Ceará.

Ana Claudia de Brito Passos , Universidade Federal do Ceará

Farmacêutica Centro de Informação de Medicamentos, Departamento de Farmácia – Universidade Federal do Ceará. Doutora em Ciências Farmacêuticas - Universidade Federal do Ceará.

Edilson Martins Rodrigues Neto, Universidade Federal do Ceará

Docente Programa de Pós-Graduação em Desenvolvimento e inovação tecnológica de medicamentos (PPGDITM) Universidade Federal do Ceará e da Pós-Graduação em Biotecnologia (PPGBIOTEC) da Universidade Estadual do Ceará. Doutor em Farmacologia – Universidade Federal do Ceará.

Mirian Parente Monteiro, Universidade Federal do Ceará

Professora Titular Departamento de Farmácia - Universidade Federal do Ceará. Doutora em Farmacologia – Universidade Federal do Ceará.

Maria Augusta Drago Ferreira, Universidade Federal do Ceará

Farmacêutica Centro de Informação de Medicamentos, Departamento de Farmácia – Universidade Federal do Ceará. Doutora em Ciências Farmacêuticas - Universidade Federal do Ceará.

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Published

2025-11-23

How to Cite

Silva, M. J., Passos , A. C. de B., Rodrigues Neto, E. M., Monteiro, M. P., & Ferreira, M. A. D. (2025). Characteristics and factors related to tramadol abuse: an integrative review : Características e fatores relacionados ao abuso de tramadol: uma revisão integrativa . Saúde E Pesquisa, 18, e13273. https://doi.org/10.17765/2176-9206.2025v18e13273

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