EVALUATION OF POTENTIAL DRUG INTERACTIONS IN PRESCRIPTIONS FOR PATIENTS IN INTENSIVE CARE UNITS

  • Cristiane Carla Dressler Garske Universidade Santa Cruz do Sul (UNISC) Hospital Santa Cruz
  • Betina Brixner Universidade de Santa Cruz do Sul (UNISC) Hospital Santa Cruz
  • Alice Pereira Freitas Universidade de Santa Cruz do Sul (UNISC) Hospital Santa Cruz
  • Ana Paula Helfer Schneider Universidade do Vale do Rio dos Sinos Universidade de Santa Cruz do Sul (UNISC)
Keywords: Critical care, Drug prescriptions, Drug interactions

Abstract

The identification and the interaction of drugs are directly related to patient´s safety and are highly relevant within the hospital. Current analysis identifies and evaluates potential drugs interactions within prescribed pharmacotherapy. The study, undertaken between August and December 2015, comprises 308 prescriptions of 195 patients hospitalized in the UTI of a university hospital. Micromedex® database identified interactions. Further, 101 out of 308 prescriptions revealed at least one drug interaction, with a total of 173 interactions with 71 patients, of which 43 were males with an average age of 61,9 years. Mean hospitalization period in the ICUs was 7 days. The 101 prescriptions with drug interactions totaled 1,349 drugs, at an average of 13,3 drugs/patient/day. The identification of these interactions avoids therapeutic failure and toxicity.

Author Biographies

Cristiane Carla Dressler Garske, Universidade Santa Cruz do Sul (UNISC) Hospital Santa Cruz
Graduada no curso de Farmácia pela Universidade de Santa Cruz do Sul (UNISC), Brasil.
Betina Brixner, Universidade de Santa Cruz do Sul (UNISC) Hospital Santa Cruz
Farmacêutica especialista em análises clínicas e toxicológicas pela Universidade de Santa Cruz do Sul (UNISC), Brasil.
Alice Pereira Freitas, Universidade de Santa Cruz do Sul (UNISC) Hospital Santa Cruz
Graduada no curso de Farmácia pela Universidade de Santa Cruz do Sul (UNISC), Brasil.
Ana Paula Helfer Schneider, Universidade do Vale do Rio dos Sinos Universidade de Santa Cruz do Sul (UNISC)
Farmacêutica; Mestre pelo Programa de Pós-Graduação em Saúde Coletiva na Universidade do Vale do Rio dos Sinos (UNISINOS), Brasil.
Published
2017-03-29
Section
Artigos Originas - Promoção da Saúde