Potential nutrient-drug interactions in pediatric patients from a University Hospital

Authors

DOI:

https://doi.org/10.17765/2176-9206.2021v14n1.e7775

Keywords:

Children, Drug interactions, Nutrition therapy

Abstract

The drug-nutrient interaction has aroused interest in research in the area of nutrition in order to avoid unwanted responses to nutritional therapy. In children, the failure to provide adequate nutrients can adversely affect both weight development and growth. To investigate the potential drug-nutrient interactions that occur in hospitalized pediatric patients. Descriptive and cross - sectional study with non - probabilistic sampling for convenience. The research was carried out by consulting the medical records and information of the nutrition service of the pediatrics sector of the University Hospital of the Federal University of Maranhão, in the Maternal and Child Unit, from August to November 2018. For the identification of potential interactions the website www.interacoesmedicamentosas.com.br and relevant scientific literature were used. A descriptive analysis of the results was performed, being presented by means of percentages and frequency distribution of the variables involved. The prescriptions of 76 patients were verified, with a mean of 28.3 ± 37.2 months. Of these, 50% were males. The mean number of prescriptions was 5.98. Among the 76 individuals, 60 (78.9%) observed possible interactions, and one patient presented five and four patients presented four. The results presented in this study reinforce the need for future research that may guide patient care aiming at the standardization of drug administration simultaneously to enteral nutrition to avoid drug-nutrient interactions in order to obtain the desired clinical results.

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Author Biographies

Yalla Diniz Santiago, Universidade Federal do Maranhão - UFMA

Resident in the Multiprofessional Residency Program in Child Health Care at the University Hospital of the Federal University of Maranhão (UFMA), São Luís (MA), Brazil.

Bruna Renata Fernandes Pires , Universidade Federal do Maranhão - UFMA

Master in Public Health and Nutritionist at the University Hospital of the Federal University of Maranhão (UFMA), São Luís (MA), Brazil.

Ilka Kassandra Pereira Belfort, Universidade Federal do Maranhão - UFMA

PhD student at the Northeast Biotechnology Network (RENORBIO) at the Federal University of Maranhão (UFMA), São Luís (MA), Brazil.

Sally Cristina Moutinho Monteiro, Universidade Federal do Maranhão - UFMA

Associate Professor at the Department of Pharmacy and at the Postgraduate Program in Adult Health (PPGSAD) at the Federal University of Maranhão (UFMA), São Luís (MA), Brazil.

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Published

2021-02-26

How to Cite

Santiago, Y. D., Pires , B. R. F. ., Belfort, I. K. P., & Monteiro, S. C. M. (2021). Potential nutrient-drug interactions in pediatric patients from a University Hospital. Saúde E Pesquisa, 14(1), 125–132. https://doi.org/10.17765/2176-9206.2021v14n1.e7775

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Artigos Originais