Morphometric Analysis of Nadh-Diaphorase Positive Neurons of the Jejunum of Wistar Rats at Different Ages

Authors

  • Evanilde Buzzo Romano Universidade Estadual de Maringá - UEM
  • Maria Raquel Marçal Natali Universidade Estadual de Maringá - UEM
  • Joici Carvalho Leite Universidade Estadual de Maringá - UEM
  • Lilian Brites Campos Universidade Estadual de Maringá - UEM
  • Evandro José Beraldi Universidade Estadual de Maringá - UEM

Keywords:

Wistar Rats, Myenteric Neurons, Jejunum, Morphometry, Aging.

Abstract

The enteric nervous system is a division of the independent nervous system, consisting of the ganglionated myenteric and submucous plexuses. It acts by regulating the functions of the gastrointestinal tract, and from adulthood, suffers a continual process of neurodegeneration. Aging involves changes in certain aspects of gastrointestinal structure and function, resulting in a reduction in the peristalsis frequency and amplitude, as well as complications in nutrients digestion and absorption. So it was decided to study the NADH density -diaphorase positive neuronal plexus of jejunum in rats of different ages (21, 60, 90, 210 days), using the NADH-diaphorase histochemical method in membrane preparations of jejunum in rats Wistar. By morphometry nitrergic neurons subpopulation of the old mice jejunum, positive for NADH-diaphorase technique, the results of this study demonstrate that there is a natural increase in the area of neurons in the first weeks of life. Upon adulthood, the mean area of neurons is diminished, associated with the onset of neuronal loss and remains without significant changes during the rest of the animal's life.

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Author Biographies

Evanilde Buzzo Romano, Universidade Estadual de Maringá - UEM

D

Maria Raquel Marçal Natali, Universidade Estadual de Maringá - UEM

Doutora em Ciências Biológicas pela Universidade Estadual Paulista "Júlio de Mesquita Filho" - UNESP. Docente em Histologia na Universidade Estadual de Maringá - UEM. E-mail: [email protected]

Joici Carvalho Leite, Universidade Estadual de Maringá - UEM

Graduada em Ciências Biológicas pela Universidade Estadual de Maringá - UEM. E-mail: [email protected]

Lilian Brites Campos, Universidade Estadual de Maringá - UEM

Mestranda em Biologia Celular pela Universidade Estadual de Maringá - UEM. E-mail: [email protected]

Evandro José Beraldi, Universidade Estadual de Maringá - UEM

Mestrando em Biologia Celular pela Universidade Estadual de Maringá - UEM. E-mail: [email protected]

How to Cite

Romano, E. B., Natali, M. R. M., Leite, J. C., Campos, L. B., & Beraldi, E. J. (2010). Morphometric Analysis of Nadh-Diaphorase Positive Neurons of the Jejunum of Wistar Rats at Different Ages. Saúde E Pesquisa, 3(1). Retrieved from https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/1490

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