Liposomal iron supplementation in women of reproductive age: analysis of biochemical parameters and symptoms

Suplementação de ferro lipossomal em mulheres na idade reprodutiva: análise de parâmetros bioquímicos e sintomas

Authors

DOI:

https://doi.org/10.17765/2176-9206.2025v18e13385

Keywords:

Nutritional supplements, Iron, Iron Deficiency, Women

Abstract

This study investigates the effects of liposomal iron supplementation in women of reproductive age, focusing on biochemical parameters and clinical symptoms. This interventional study, conducted in Belo Horizonte, Brazil, included 20 women of reproductive age with regular menstrual cycles who received a daily supplementation of 30 mg of liposomal iron for 60 days. Clinical symptoms, dietary intake, and laboratory tests (transferrin saturation, ferritin, hemoglobin, and C-reactive protein) were evaluated at baseline and at the end of the study. Liposomal iron supplementation increased hemoglobin (p=0.002) and ferritin (p=0.031) but had no effect on transferrin saturation (p=0.541). Symptoms such as fatigue, weakness, hair loss, nausea, and constipation improved. Thus, the present study demonstrates that liposomal iron supplementation improved iron metabolism markers and clinical symptoms in women of reproductive age.

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Author Biographies

Maria Isabel Teixeira de Aquino, Faculdade de Minas

Nutrition student, Nutrition Department, Faculdade de Minas FAMINAS-BH

Rafaela Brígido Ferreira da Costa, Faculdade de Minas

Nutrition student, Nutrition Department, Faculdade de Minas FAMINAS-BH.

João Pedro Pessoa de Souza, Faculdade de Minas

Undergraduate in Nutrition, Department of Nutrition, Faculty of Minas FAMINAS-BH.

Vanessa Patrocínio de Oliveira, Faculdade de Minas

Master in Nutrition Sciences from the Federal University of Viçosa. Academic coordinator and assistant professor in the Nutrition course, Department of Nutrition, at the Faculty of Minas FAMINAS-BH.

Gabriel Piccinini de Carvalho, Faculdade de Saúde Avançada

Professor and Coordinator, Department of Nutrition, Faculty of Advanced Health.

Marcio Leandro Ribeiro de Souza, Faculdade de Minas

PhD in Adult Health from the Faculty of Medicine at UFMG. Full Professor in the undergraduate course in Nutrition, Department of Nutrition, at the Faculty of Minas FAMINAS-BH.

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Published

2025-11-22

How to Cite

Aquino, M. I. T. de, Costa, R. B. F. da, Souza, J. P. P. de, Oliveira, V. P. de, Carvalho, G. P. de, & Souza, M. L. R. de. (2025). Liposomal iron supplementation in women of reproductive age: analysis of biochemical parameters and symptoms : Suplementação de ferro lipossomal em mulheres na idade reprodutiva: análise de parâmetros bioquímicos e sintomas . Saúde E Pesquisa, 18, e13385. https://doi.org/10.17765/2176-9206.2025v18e13385

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Artigos Originais