Impacto do uso de corticosteróides e sulfato de magnésio em recém-nascidos de 32 semanas

Bruna Poerner; Rafaela Rossi; Manoela Duarte Selbach; Eloisa Celestino Shigeoka; Jean Carl Silva

doi:10.17765/2176-9206.2026v19e13439

Authors

Bruna Poerner Universidade da Região de Joinville https://orcid.org/0000-0001-7162-5604
Rafaela Rossi Universidade da Região de Joinville https://orcid.org/0000-0003-0435-3033
Manoela Duarte Selbach Universidade da Região de Joinville https://orcid.org/0000-0001-6593-4734
Eloisa Celestino Shigeoka Universidade da Região de Joinville https://orcid.org/0000-0001-7234-7896
Jean Carl Silva Universidade da Região de Joinville https://orcid.org/0000-0002-3094-8180

DOI:

https://doi.org/10.17765/2176-9206.2026v19e13439

Keywords:

Coricosteroids, Gestational, Magnesium Sulfate

Abstract

The objective of this study was to evaluate the impact of corticosteroid use and magnesium sulfate administration in newborns at 32 weeks of gestation. This was a cross-sectional study including 132 patients divided into three groups: complete cycle of corticosteroid and magnesium sulfate (n = 62), corticosteroid only (n = 22), and no treatment (n = 48), and the outcomes assessed were neonatal intensive care unit admission (NICU), respiratory distress syndrome (RDS), mechanical ventilation (MV), neurological impairment (NI), and death, with data analyzed at a significance level of p ? 0.05. The outcomes differed mainly regarding the need for NICU admission, which was less frequent in the complete cycle group (n = 3) and in the corticosteroid-only group (n = 1) compared with the no-treatment group (n = 10), and there was also a lower need for mechanical ventilation in the complete cycle group (n = 5) and in the corticosteroid-only group (n = 4). It is concluded that corticosteroid therapy, whether associated or not with magnesium sulfate, had a positive impact by reducing the need for NICU admission and mechanical ventilation.

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Author Biographies

Bruna Poerner, Universidade da Região de Joinville

Medical student in her 9th semester at the University of the Joinville Region - UNIVILLE

Rafaela Rossi, Universidade da Região de Joinville

Undergraduate medical student in the 11th semester at the University of the Joinville Region - UNIVILLE

Manoela Duarte Selbach, Universidade da Região de Joinville

Undergraduate medical student in the 11th semester at the University of the Joinville Region - UNIVILLE

Eloisa Celestino Shigeoka , Universidade da Região de Joinville

Medical student in her 9th semester at the University of the Joinville Region - UNIVILLE

Jean Carl Silva, Universidade da Região de Joinville

Medical Doctor from the Federal University of Santa Catarina - UFSC (1988), Master's degree in Health and Environment from the University of the Joinville Region - UNIVILLE (2002) and Doctorate in Medical Sciences from the Federal University of São Paulo - UNIFESP (2005). Currently, he holds the position of coordinator of the high-risk pregnancy service at the Darcy Maternity Hospital and the UNIMED Hospital Center. In addition, he works as a researcher at the Atena Research Center, located at the Darcy Vargas Maternity Hospital. As part of his academic contribution, he is a Professor of Obstetrics in the Medicine course and a Professor in the Postgraduate course in Health and Environment at the University of the Joinville Region - UNIVILLE. In clinical practice, he works as a Gynecologist and Obstetrician at the Vitae Maternal and Child Clinic.

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