Padrão prescritivo de medicamentos para hipertensão arterial sistêmica na atenção primária em saúde: revisão sistemática e meta-análise

Palavras-chave: Atenção primária em saúde, Diretrizes para prática, Hipertensão arterial sistêmica, Prescrição de medicamentos, Revisão sistemática

Resumo

Investigamos publicações científicas sobre o padrão prescritivo de medicamentos para hipertensão arterial sistêmica e uso de diretrizes na atenção primária em saúde por revisão sistemática e meta-análise. Os artigos foram selecionados nas bases de dados PubMed, Web of Science e LILACS, de acordo com as declarações PRISMA, de 2004 a 2020. A revisão sistemática mostrou um padrão de prescrição superior para terapia combinada (52,9%). A metanálise confirmou a superioridade para a terapia combinada (OR 1,76; IC 1,29 - 2,41). Foi observada maior prevalência de monoterapia no estudo Sueco (98%) e terapia combinada no Nigeriano (98%). Maior frequência prescritiva de inibidores da enzima de conversão da angiotensina em Trinidade (64%); diuréticos (64%), betabloqueadores (63%) e bloqueadores dos canais de cálcio (53%) na Nigéria; e bloqueadores dos receptores da angiotensina (43%) em Portugal. Quanto ao uso das diretrizes, 53% dos estudos relataram a sua utilização na prescrição de anti-hipertensivos na atenção primária em saúde.

Biografia do Autor

Edilson Almeida de Oliveira, Universidade Estadual de Maringá
Doutor pelo Programa de Pós-graduação em Biociências e Fisiopatologia (PBF) da Universidade Estadual de Maringá (UEM). Farmacêutico da Policlínica Dr Primo Marcelo Monteschio, UBS Zona Sul, SMS, PMM, , Maringá (PR), Brasil.
Iris Heloísa Pereira Guerra, State University of Maringá
Mestre pelo Programa de Pós-graduação em Biociências e Fisiopatologia (PBF) da Universidade Estadual de Maringá (UEM), Maringá (PR), Brasil.
Débora Canassa Volpato, State University of Maringá
Mestre pelo Programa de Pós-graduação em Biociências e Fisiopatologia (PBF) da Universidade Estadual de Maringá (UEM), Maringá (PR), Brasil.
Rogério Toshiro Passos Okawa, State University of Maringá
Professor do Departamento de Medicina, Universidade Estadual de Maringá (UEM), Maringá (PR), Brasil.
Kesia Palma-Rigo , State University of Maringá
Professor colaborador do Programa de Pós-graduação em Biociências e Fisiopatologia (PBF) da Universidade Estadual de Maringá (UEM), Maringá (PR), Brasil.
Thaís da Silva Santos, State University of Maringá
Mestre pelo Programa de Pós-graduação em Biociências e Fisiopatologia (PBF) da Universidade Estadual de Maringá (UEM), Maringá (PR), Brasil.
Jorge Juarez Vieira Teixeira, State University of Maringá
Professor permanente do Programa de Pós-graduação em Biociências e Fisiopatologia (PBF) da Universidade Estadual de Maringá (UEM), Maringá (PR), Brasil.

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Publicado
2021-02-26
Seção
Artigos de Revisão - Promoção da Saúde